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Phosphatidic Acid Mediates the Nem1-Spo7/Pah1 Phosphatase Cascade in Yeast Lipid Synthesis

In the yeast Saccharomyces cerevisiae, the PAH1-encoded Mg(2+)-dependent phosphatidate (PA) phosphatase Pah1 regulates the bifurcation of PA to diacylglycerol (DAG) for triacylglycerol (TAG) synthesis and to CDP-DAG for phospholipid synthesis. Pah1 function is mainly regulated via control of its cel...

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Detalles Bibliográficos
Autores principales: Kwiatek, Joanna M., Gutierrez, Bryan, Izgu, Enver Cagri, Han, Gil-Soo, Carman, George M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587005/
https://www.ncbi.nlm.nih.gov/pubmed/36314526
http://dx.doi.org/10.1016/j.jlr.2022.100282