Pentacyclic triterpenoid ursolic acid interferes with mast cell activation via a lipid-centric mechanism affecting FcεRI signalosome functions

Pentacyclic triterpenoids, including ursolic acid (UA), are bioactive compounds with multiple biological activities involving anti-inflammatory effects. However, the mode of their action on mast cells, key players in the early stages of allergic inflammation, and underlying molecular mechanisms rema...

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Detalles Bibliográficos
Autores principales: Shaik, Gouse M., Draberova, Lubica, Cernohouzova, Sara, Tumova, Magda, Bugajev, Viktor, Draber, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587013/
https://www.ncbi.nlm.nih.gov/pubmed/36115460
http://dx.doi.org/10.1016/j.jbc.2022.102497

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587013/
https://www.ncbi.nlm.nih.gov/pubmed/36115460
http://dx.doi.org/10.1016/j.jbc.2022.102497

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