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Construction of a bioluminescence-based assay for bitter taste receptors (TAS2Rs)
In humans, a family of 25 bitter taste receptors (TAS2Rs) mediates bitter taste perception. A common approach to characterize bitter causative agents involves expressing TAS2Rs and the appropriate signal transducers in heterologous cell systems, and monitoring changes in the intracellular free calci...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587021/ https://www.ncbi.nlm.nih.gov/pubmed/36271274 http://dx.doi.org/10.1038/s41598-022-21678-3 |