Serine 13 of the human cytomegalovirus viral cyclin-dependent kinase UL97 is required for regulatory protein 14-3-3 binding and UL97 stability

The human cytomegalovirus (HCMV) UL97 protein is a conserved herpesvirus protein kinase (CHPK) and a viral cyclin-dependent kinase (v-CDK). However, mechanisms regulating its activity in the context of infection are unknown. Here, we identified several cellular regulatory 14-3-3 proteins as UL97-int...

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Detalles Bibliográficos
Autores principales: Iwahori, Satoko, Umaña, Angie C., Kalejta, Robert F., Murata, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587022/
https://www.ncbi.nlm.nih.gov/pubmed/36150501
http://dx.doi.org/10.1016/j.jbc.2022.102513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587022/
https://www.ncbi.nlm.nih.gov/pubmed/36150501
http://dx.doi.org/10.1016/j.jbc.2022.102513

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