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In silico investigations identified Butyl Xanalterate to competently target CK2α (CSNK2A1) for therapy of chronic lymphocytic leukemia

Chronic lymphocytic leukemia (CLL) is an incurable malignancy of B-cells. In this study, bioinformatics analyses were conducted to identify possible pathogenic roles of CK2α, which is a protein encoded by CSNK2A1, in the progression and aggressiveness of CLL. Furthermore, various computational tools...

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Detalles Bibliográficos
Autores principales: Alsagaby, Suliman A., Iqbal, Danish, Ahmad, Iqrar, Patel, Harun, Mir, Shabir Ahmad, Madkhali, Yahya Awaji, Oyouni, Atif Abdulwahab A., Hawsawi, Yousef M., Alhumaydhi, Fahad A., Alshehri, Bader, Alturaiki, Wael, Alanazi, Bader, Mir, Manzoor Ahmad, Al Abdulmonem, Waleed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587039/
https://www.ncbi.nlm.nih.gov/pubmed/36271116
http://dx.doi.org/10.1038/s41598-022-21546-0