Single cell transcriptomic profiling of a neuron-astrocyte assembloid tauopathy model

The use of iPSC derived brain organoid models to study neurodegenerative disease has been hampered by a lack of systems that accurately and expeditiously recapitulate pathogenesis in the context of neuron-glial interactions. Here we report development of a system, termed AstTau, which propagates tox...

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Detalles Bibliográficos
Autores principales: Rickner, Hannah Drew, Jiang, Lulu, Hong, Rui, O’Neill, Nicholas K., Mojica, Chromewell A., Snyder, Benjamin J., Zhang, Lushuang, Shaw, Dipan, Medalla, Maria, Wolozin, Benjamin, Cheng, Christine S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587045/
https://www.ncbi.nlm.nih.gov/pubmed/36271092
http://dx.doi.org/10.1038/s41467-022-34005-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587045/
https://www.ncbi.nlm.nih.gov/pubmed/36271092
http://dx.doi.org/10.1038/s41467-022-34005-1

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