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Single cell transcriptomic profiling of a neuron-astrocyte assembloid tauopathy model
The use of iPSC derived brain organoid models to study neurodegenerative disease has been hampered by a lack of systems that accurately and expeditiously recapitulate pathogenesis in the context of neuron-glial interactions. Here we report development of a system, termed AstTau, which propagates tox...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587045/ https://www.ncbi.nlm.nih.gov/pubmed/36271092 http://dx.doi.org/10.1038/s41467-022-34005-1 |