A TNFR1–UBCH10 axis drives lung squamous cell carcinoma dedifferentiation and metastasis through a cell-autonomous signaling loop

Tumor necrosis factor receptor 1 (TNFR1), encoded by TNFRSF1A, is a critical transducer of inflammatory pathways, but its physiological role in human cancer is not completely understood. Here, we observed high expression of TNFR1 in many human lung squamous cell carcinoma (SCCs) samples and in spont...

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Detalles Bibliográficos
Autores principales: Xiao, Zuoxiang, Shi, Gongping, Xi, Sichuan, Singh, Amit Kumar, Willette-Brown, Jami, Li, Xin, Zhu, Feng, Su, Ling, Wu, Xiaolin, Schrump, David S., Hu, Yinling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587052/
https://www.ncbi.nlm.nih.gov/pubmed/36270982
http://dx.doi.org/10.1038/s41419-022-05308-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587052/
https://www.ncbi.nlm.nih.gov/pubmed/36270982
http://dx.doi.org/10.1038/s41419-022-05308-4

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