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Comparative transcriptomic analysis of whole blood mycobacterial growth assays and tuberculosis patients’ blood RNA profiles

In vitro whole blood infection models are used for elucidating the immune response to Mycobacterium tuberculosis (Mtb). They exhibit commonalities but also differences, to the in vivo blood transcriptional response during natural human Mtb disease. Here, we present a description of concordant and di...

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Detalles Bibliográficos
Autores principales: Bachanová, Petra, Cheyne, Ashleigh, Broderick, Claire, Newton, Sandra M., Levin, Michael, Kaforou, Myrsini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587058/
https://www.ncbi.nlm.nih.gov/pubmed/36271270
http://dx.doi.org/10.1038/s41598-022-20409-y