Apalutamide and autophagy inhibition in a xenograft mouse model of human prostate cancer

BACKGROUND: Apalutamide (APA) is a next-generation androgen receptor antagonist for the treatment of advanced prostate cancer. We have previously shown that upregulation of autophagy is one of the mechanisms by which prostate cancer (PC) cells survive APA anti-tumor treatment in vitro. Therefore, we...

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Detalles Bibliográficos
Autores principales: Eberli, Daniel, Kranzbühler, Benedikt, Prause, Lukas, Baumgartner, Valentin, Preda, Sheryl, Sousa, Rosa, Lehner, Fabienne, Salemi, Souzan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Article – Cancer Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587065/
https://www.ncbi.nlm.nih.gov/pubmed/35751683
http://dx.doi.org/10.1007/s00432-022-04059-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587065/
https://www.ncbi.nlm.nih.gov/pubmed/35751683
http://dx.doi.org/10.1007/s00432-022-04059-1

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