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The hyaluronan-related genes HAS2, HYAL1-4, PH20 and HYALP1 are associated with prognosis, cell viability and spheroid formation capacity in ovarian cancer

PURPOSE: Hyaluronan modulates tumour progression, including cell adhesion, cohesion, proliferation and invasion, and the cancer stem cell phenotype. In ovarian cancer, high levels of stromal hyaluronan are associated with poor prognosis. In this work, hyaluronan synthases (HAS1-3) and hyaluronidases...

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Detalles Bibliográficos
Autores principales: Riecks, Jette, Parnigoni, Arianna, Győrffy, Balázs, Kiesel, Ludwig, Passi, Alberto, Vigetti, Davide, Götte, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587083/
https://www.ncbi.nlm.nih.gov/pubmed/35767191
http://dx.doi.org/10.1007/s00432-022-04127-6