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Modelling reoxygenation effects in non-small cell lung cancer cell lines and showing epithelial-mesenchymal transition

PURPOSE: Circulating tumour cells (CTCs) are a rare cell subpopulation regulated by the tumour microenvironment. In hypoxic conditions, CTCs are able to invade the lymphatic and circulatory systems leading to metastasis at distant sites. METHODS: To mimic in vivo oxygen variations and effects on CTC...

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Detalles Bibliográficos
Autores principales: Kapeleris, Joanna, Müller Bark, Juliana, Ranjit, Shanon, Richard, Derek, Vela, Ian, O’Byrne, Kenneth, Punyadeera, Chamindie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587087/
https://www.ncbi.nlm.nih.gov/pubmed/35932303
http://dx.doi.org/10.1007/s00432-022-04242-4