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Inflammatory Modulation of miR-155 Inhibits Doxorubicin-Induced Testicular Dysfunction via SIRT1/FOXO1 Pathway: Insight into the Role of Acacetin and Bacillus cereus Protease

Doxorubicin (DOX) is a chemotherapeutic agent that can disrupt testicular function leading to male infertility. This study examined the protective role of natural flavone, acacetin (ACA), and a protease of Bacillus cereus bacteria (B. cereus) as well as the potential role of miR-155/SIRT1/FOXO1 netw...

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Detalles Bibliográficos
Autores principales: Anwar, Hend Mohamed, Hamad, Sherin Ramadan, Salem, Gad Elsayed Mohamed, Soliman, Rania Hassan Mohamed, Elbaz, Eman Maher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587093/
https://www.ncbi.nlm.nih.gov/pubmed/35715546
http://dx.doi.org/10.1007/s12010-022-03992-8