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Inhibition of angiogenesis and tumor progression of MK-0429, an integrin αvβ(3) antagonist, on oral squamous cell carcinoma

PURPOSE: Integrin αvβ(3) is an essential molecule for tumor angiogenesis. This study aimed to investigate the anti-tumor effect of MK-0429, an integrin αvβ(3) antagonist, on oral squamous cell carcinoma (OSCC) through its inhibitory effect on angiogenesis. METHODS: In this study, we investigated the...

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Detalles Bibliográficos
Autores principales: Nakagawa, Takayuki, Ohta, Kouji, Naruse, Takako, Sakuma, Miyuki, Fukada, Syohei, Yamakado, Nao, Akagi, Misaki, Sasaki, Kazuki, Niwata, Chieko, Ono, Shigehiro, Aikawa, Tomonao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587112/
https://www.ncbi.nlm.nih.gov/pubmed/35713706
http://dx.doi.org/10.1007/s00432-022-04100-3