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Fluconazole Is Neuroprotective via Interactions with the IGF-1 Receptor

There is a continuing unmet medical need to develop neuroprotective strategies to treat neurodegenerative disorders. To address this need, we screened over 2000 compounds for potential neuroprotective activity in a model of oxidative stress and found that numerous antifungal agents were neuroprotect...

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Detalles Bibliográficos
Autores principales: Toodle, Valerie, Lee, Myoung-Hwa, Bachani, Muzna, Ruffin, April, Vivekanandhan, Sneha, Malik, Nasir, Wang, Tongguang, Johnson, Tory P., Nath, Avindra, Steiner, Joseph P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587198/
https://www.ncbi.nlm.nih.gov/pubmed/35831747
http://dx.doi.org/10.1007/s13311-022-01265-0