Epstein Barr virus-mediated transformation of B cells from XIAP-deficient patients leads to increased expression of the tumor suppressor CADM1

X-linked lymphoproliferative disease (XLP) is either caused by loss of the SLAM-associated protein (SAP; XLP-1) or the X-linked inhibitor of apoptosis (XIAP; XLP-2). In both instances, infection with the oncogenic human Epstein Barr virus (EBV) leads to pathology, but EBV-associated lymphomas only e...

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Detalles Bibliográficos
Autores principales: Engelmann, Christine, Schuhmachers, Patrick, Zdimerova, Hana, Virdi, Sanamjeet, Hauri-Hohl, Mathias, Pachlopnik Schmid, Jana, Grundhoff, Adam, Marsh, Rebecca A., Wong, Wendy Wei-Lynn, Münz, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587222/
https://www.ncbi.nlm.nih.gov/pubmed/36270981
http://dx.doi.org/10.1038/s41419-022-05337-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587222/
https://www.ncbi.nlm.nih.gov/pubmed/36270981
http://dx.doi.org/10.1038/s41419-022-05337-z

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