Wnt4 is heterogeneously activated in maturing β-cells to control calcium signaling, metabolism and function

Diabetes is a multifactorial disorder characterized by loss or dysfunction of pancreatic β-cells. β-cells are heterogeneous, exhibiting different glucose sensing, insulin secretion and gene expression. They communicate with other endocrine cell types via paracrine signals and between β-cells via gap...

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Detalles Bibliográficos
Autores principales: Katsumoto, Keiichi, Yennek, Siham, Chen, Chunguang, Silva, Luis Fernando Delgadillo, Traikov, Sofia, Sever, Dror, Azad, Ajuna, Shan, Jingdong, Vainio, Seppo, Ninov, Nikolay, Speier, Stephan, Grapin-Botton, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587236/
https://www.ncbi.nlm.nih.gov/pubmed/36271049
http://dx.doi.org/10.1038/s41467-022-33841-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587236/
https://www.ncbi.nlm.nih.gov/pubmed/36271049
http://dx.doi.org/10.1038/s41467-022-33841-5

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