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Cellular basis of enhanced humoral immunity to SARS-CoV-2 upon homologous or heterologous booster vaccination analyzed by single-cell immune profiling

SARS-CoV-2 vaccine booster dose can induce a robust humoral immune response, however, its cellular mechanisms remain elusive. Here, we investigated the durability of antibody responses and single-cell immune profiles following booster dose immunization, longitudinally over 6 months, in recipients of...

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Detalles Bibliográficos
Autores principales: Ai, Jingwen, Guo, Jingxin, Zhang, Haocheng, Zhang, Yi, Yang, Haochen, Lin, Ke, Song, Jieyu, Fu, Zhangfan, Fan, Mingxiang, Zhang, Qiran, Wang, Hongyu, Zhao, Yuanhan, He, Zhangyufan, Cui, An, Zhou, Yang, Wu, Jing, Zhou, Mingzhe, Yuan, Guanmin, Kang, Boxi, Zhao, Ning, Xu, Yuanyuan, Zhu, Mengqi, Wang, Youhong, Zhang, Zemin, Jiang, Ning, Qiu, Chao, Xu, Chenqi, Zhang, Wenhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587260/
https://www.ncbi.nlm.nih.gov/pubmed/36270988
http://dx.doi.org/10.1038/s41421-022-00480-5