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Stem cell-based multi-tissue platforms to model human autoimmune diabetes

BACKGROUND: Type 1 diabetes (T1D) is an autoimmune disease in which pancreatic insulin-producing β cells are specifically destroyed by the immune system. Understanding the initiation and progression of human T1D has been hampered by the lack of appropriate models that can reproduce the complexity an...

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Detalles Bibliográficos
Autores principales: Leavens, Karla F., Alvarez-Dominguez, Juan R., Vo, Linda T., Russ, Holger A., Parent, Audrey V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587366/
https://www.ncbi.nlm.nih.gov/pubmed/36209784
http://dx.doi.org/10.1016/j.molmet.2022.101610