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Performance of Nanopore and Illumina Metagenomic Sequencing for Pathogen Detection and Transcriptome Analysis in Infantile Central Nervous System Infections

BACKGROUND: Infantile central nervous system infections (CNSIs) can be life-threatening and cause severe sequelae. However, the causative microorganism remains unknown in >40% of patients with aseptic infections. This study aimed to analyze the metagenome for detection of pathogens and the transc...

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Detalles Bibliográficos
Autores principales: Horiba, Kazuhiro, Torii, Yuka, Aizawa, Yuta, Yamaguchi, Makoto, Haruta, Kazunori, Okumura, Toshihiko, Suzuki, Takako, Kawano, Yoshihiko, Kawada, Jun-ichi, Hara, Shinya, Saitoh, Akihiko, Giske, Christian G, Ogi, Tomoo, Ito, Yoshinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587384/
https://www.ncbi.nlm.nih.gov/pubmed/36299531
http://dx.doi.org/10.1093/ofid/ofac504