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Enriched enrollment randomized double-blind placebo-controlled cross-over trial with phenytoin cream in painful chronic idiopathic axonal polyneuropathy (EPHENE): a study protocol

BACKGROUND: Patients with chronic idiopathic axonal polyneuropathy (CIAP) can have neuropathic pain that significantly impacts quality of life. Oral neuropathic pain medication often has insufficient pain relief and side effects. Topical phenytoin cream could circumvent these limitations. The primar...

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Detalles Bibliográficos
Autores principales: Kopsky, David J., van Eijk, Ruben P. A., Warendorf, Janna K., Keppel Hesselink, Jan M., Notermans, Nicolette C., Vrancken, Alexander F. J. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587538/
https://www.ncbi.nlm.nih.gov/pubmed/36273216
http://dx.doi.org/10.1186/s13063-022-06806-8