G6PD promotes cell proliferation and dexamethasone resistance in multiple myeloma via increasing anti-oxidant production and activating Wnt/β-catenin pathway

BACKGROUND: Glucose-6-phosphate dehydrogenase (G6PD) as the rate-limiting enzyme in the pentose phosphate pathway (PPP) is well-established as an aberrantly expressed protein in numerous clinical diseases; however, its role in cancer, specifically in multiple myeloma (MM) remains elusive. METHODS: I...

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Detalles Bibliográficos
Autores principales: Li, Rui, Ke, Mengying, Qi, Mingming, Han, Zhenru, Cao, Yuhao, Deng, Zhendong, Qian, Jinjun, Yang, Ye, Gu, Chunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587560/
https://www.ncbi.nlm.nih.gov/pubmed/36271440
http://dx.doi.org/10.1186/s40164-022-00326-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587560/
https://www.ncbi.nlm.nih.gov/pubmed/36271440
http://dx.doi.org/10.1186/s40164-022-00326-6

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