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Simiao pill inhibits epithelial mesenchymal transition in a mouse model of chronic hyperuricemic nephropathy by inhibiting NLRP3 inflammasome activation

BACKGROUND: Simiao pill module (SMM), a traditional Chinese medicine formula, has been widely used to treat gout and gouty arthritis. The goal of this study was to investigate the effects of SMM on epithelial-mesenchymal transition (EMT) and activation of NLR family pyrin domain containing 3 (NLRP3)...

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Detalles Bibliográficos
Autores principales: Shui, Guangxing, Cai, Zheyi, Wang, Feng, Chen, Ting, Huang, Xueyuan, Cai, Yun, Mi, Xiuhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587568/
https://www.ncbi.nlm.nih.gov/pubmed/36271349
http://dx.doi.org/10.1186/s12906-022-03757-0