Cargando…

Linear and conformational determinants of visceral leishmaniasis diagnostic antigens rK28 and rK39

BACKGROUND: Recombinant antigens rK39 (based on kinesin sequence) and rK28 (comprising kinesin and HASPB sequences) are a mainstay of serological diagnosis for visceral leishmaniasis (VL). However, their key epitopes and the significance of their structural conformation are not clearly defined, part...

Descripción completa

Detalles Bibliográficos
Autores principales: Simonson, Poppy, Bhattacharyya, Tapan, El-Safi, Sayda, Miles, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587664/
https://www.ncbi.nlm.nih.gov/pubmed/36273150
http://dx.doi.org/10.1186/s13071-022-05495-1