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Linear and conformational determinants of visceral leishmaniasis diagnostic antigens rK28 and rK39
BACKGROUND: Recombinant antigens rK39 (based on kinesin sequence) and rK28 (comprising kinesin and HASPB sequences) are a mainstay of serological diagnosis for visceral leishmaniasis (VL). However, their key epitopes and the significance of their structural conformation are not clearly defined, part...
Autores principales: | Simonson, Poppy, Bhattacharyya, Tapan, El-Safi, Sayda, Miles, Michael A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587664/ https://www.ncbi.nlm.nih.gov/pubmed/36273150 http://dx.doi.org/10.1186/s13071-022-05495-1 |
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