Fenretinide combines perturbation of signaling kinases, cell–extracellular matrix interactions and matrix metalloproteinase activation to inhibit invasion in oral squamous cell carcinoma cells

Basement membrane invasion defines malignant transformation of surface premalignancy. Treatment of oral squamous cell carcinoma (OSCC) cells with the synthetic vitamin A derivative, fenretinide (4HPR), induces numerous cancer-preventive effects including suppression of basement membrane invasion, el...

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Detalles Bibliográficos
Autores principales: Wang, Daren, Pei, Ping, Shea, Fortune F, Bissonnette, Caroline, Nieto, Kari, Din, Corrine, Liu, Yayuan, Schwendeman, Steven P, Lin, Yan X, Spinney, Richard, Mallery, Susan R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Inflammation, Microenvironment and Prevention
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587683/
https://www.ncbi.nlm.nih.gov/pubmed/35974187
http://dx.doi.org/10.1093/carcin/bgac070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587683/
https://www.ncbi.nlm.nih.gov/pubmed/35974187
http://dx.doi.org/10.1093/carcin/bgac070

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