Pathogenicity Reclassification of Genetic Variants Related to Early-Onset Breast Cancer among Women of Mongoloid Origin

BACKGROUND: Germline alterations in BRCA1, BRCA2, and other genes are responsible for early-onset breast cancer. However, up to 20% of molecular tests report genetic variant of unknown significance (VUS) or novel variants that have never been previously described and their clinical significance are...

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Detalles Bibliográficos
Autores principales: Gervas, Polina, Molokov, Aleksey, Babyshkina, Nataliya, Kiselev, Artem, Zarubin, Aleksei, Yumov, Evgeny, Pisareva, Lubov, Choynzonov, Evgeny, Cherdyntseva, Nadezda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587833/
https://www.ncbi.nlm.nih.gov/pubmed/35763645
http://dx.doi.org/10.31557/APJCP.2022.23.6.2027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587833/
https://www.ncbi.nlm.nih.gov/pubmed/35763645
http://dx.doi.org/10.31557/APJCP.2022.23.6.2027

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