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Relationship between Bax and Bcl-2 Protein Expression and Outcome of Induction Phase Chemotherapy in Pediatric Acute Lymphoblastic Leukemia

BACKGROUND: Overexpression of the antiapoptotic protein Bcl-2 causes apoptosis to stop and conversely the increased expression of the proapoptotic protein Bax makes lymphoblasts easy to destroy. The Bax/Bcl-2 ratio plays a role in the balance of apoptosis, immortality, resistance, and outcome of che...

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Detalles Bibliográficos
Autores principales: Cahyadi, Andi, Ugrasena, I Dewa Gede, Andarsini, Mia Ratwita, Larasati, Maria Christina Shanty, Aryati, Aryati, Arumsari, Diah Kusuma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587893/
https://www.ncbi.nlm.nih.gov/pubmed/35633553
http://dx.doi.org/10.31557/APJCP.2022.23.5.1679