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Interaction of cholinergic disruption and age on cognitive flexibility in rats

Healthy aging is associated with a functional reduction of the basal forebrain (BF) system that supplies the neurochemical acetylcholine (ACh) to the cortex, and concomitant challenges to cognition. It remains unclear how aging and ACh loss interact to shape cognition in the aging brain. We used a p...

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Detalles Bibliográficos
Autores principales: Cammarata, Celine, De Rosa, Eve D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587929/
https://www.ncbi.nlm.nih.gov/pubmed/36198843
http://dx.doi.org/10.1007/s00221-022-06472-x