Lost in promiscuity? An evolutionary and biochemical evaluation of HSD10 function in cardiolipin metabolism

Multifunctional proteins are challenging as it can be difficult to confirm pathomechanisms associated with disease-causing genetic variants. The human 17β-hydroxysteroid dehydrogenase 10 (HSD10) is a moonlighting enzyme with at least two structurally and catalytically unrelated functions. HSD10 dise...

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Detalles Bibliográficos
Autores principales: Wohlfarter, Yvonne, Eidelpes, Reiner, Yu, Ryan D., Sailer, Sabrina, Koch, Jakob, Karall, Daniela, Scholl-Bürgi, Sabine, Amberger, Albert, Hillen, Hauke S., Zschocke, Johannes, Keller, Markus A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587951/
https://www.ncbi.nlm.nih.gov/pubmed/36271951
http://dx.doi.org/10.1007/s00018-022-04579-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587951/
https://www.ncbi.nlm.nih.gov/pubmed/36271951
http://dx.doi.org/10.1007/s00018-022-04579-6

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