Haplotyping pharmacogenes using TLA combined with Illumina or Nanopore sequencing

The currently used pharmacogenetic genotyping assays offer limited haplotype information, which can potentially cause specific functional effects to be missed. This study tested if Targeted Locus Amplification (TLA), when using non-patient-specific primers combined with Illumina or Nanopore sequenci...

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Detalles Bibliográficos
Autores principales: Tilleman, Laurentijn, Rubben, Kaat, Van Criekinge, Wim, Deforce, Dieter, Van Nieuwerburgh, Filip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587992/
https://www.ncbi.nlm.nih.gov/pubmed/36273027
http://dx.doi.org/10.1038/s41598-022-22499-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587992/
https://www.ncbi.nlm.nih.gov/pubmed/36273027
http://dx.doi.org/10.1038/s41598-022-22499-0

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