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TRPM8 contributes to sex dimorphism by promoting recovery of normal sensitivity in a mouse model of chronic migraine

TRPA1 and TRPM8 are transient receptor potential channels expressed in trigeminal neurons that are related to pathophysiology in migraine models. Here we use a mouse model of nitroglycerine-induced chronic migraine that displays a sexually dimorphic phenotype, characterized by mechanical hypersensit...

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Detalles Bibliográficos
Autores principales: Alarcón-Alarcón, David, Cabañero, David, de Andrés-López, Jorge, Nikolaeva-Koleva, Magdalena, Giorgi, Simona, Fernández-Ballester, Gregorio, Fernández-Carvajal, Asia, Ferrer-Montiel, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588003/
https://www.ncbi.nlm.nih.gov/pubmed/36272975
http://dx.doi.org/10.1038/s41467-022-33835-3