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REDD1 promotes obesity-induced metabolic dysfunction via atypical NF-κB activation

Regulated in development and DNA damage response 1 (REDD1) expression is upregulated in response to metabolic imbalance and obesity. However, its role in obesity-associated complications is unclear. Here, we demonstrate that the REDD1–NF-κB axis is crucial for metabolic inflammation and dysregulatio...

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Detalles Bibliográficos
Autores principales: Lee, Dong-Keon, Kim, Taesam, Byeon, Junyoung, Park, Minsik, Kim, Suji, Kim, Joohwan, Choi, Seunghwan, Lee, Gihwan, Park, Chanin, Lee, Keun Woo, Kwon, Yong Jung, Lee, Jeong-Hyung, Kwon, Young-Guen, Kim, Young-Myeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588012/
https://www.ncbi.nlm.nih.gov/pubmed/36272977
http://dx.doi.org/10.1038/s41467-022-34110-1