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REDD1 promotes obesity-induced metabolic dysfunction via atypical NF-κB activation
Regulated in development and DNA damage response 1 (REDD1) expression is upregulated in response to metabolic imbalance and obesity. However, its role in obesity-associated complications is unclear. Here, we demonstrate that the REDD1–NF-κB axis is crucial for metabolic inflammation and dysregulatio...
Autores principales: | Lee, Dong-Keon, Kim, Taesam, Byeon, Junyoung, Park, Minsik, Kim, Suji, Kim, Joohwan, Choi, Seunghwan, Lee, Gihwan, Park, Chanin, Lee, Keun Woo, Kwon, Yong Jung, Lee, Jeong-Hyung, Kwon, Young-Guen, Kim, Young-Myeong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588012/ https://www.ncbi.nlm.nih.gov/pubmed/36272977 http://dx.doi.org/10.1038/s41467-022-34110-1 |
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