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Highly efficient hybridoma generation and screening strategy for anti-PD-1 monoclonal antibody development

Programmed cell death protein 1 (PD-1) plays a significant role in suppressing antitumor immune responses. Cancer treatment with immune checkpoint inhibitors (ICIs) targeting PD-1 has been approved to treat numerous cancers and is the backbone of cancer immunotherapy. Anti-PD-1 molecule is necessary...

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Detalles Bibliográficos
Autores principales: Phakham, Tanapati, Boonkrai, Chatikorn, Wongtangprasert, Tossapon, Audomsun, Thittaya, Attakitbancha, Chadaporn, Saelao, Pijitra, Muanwien, Phijitra, Sooksai, Sarintip, Hirankarn, Nattiya, Pisitkun, Trairak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588028/
https://www.ncbi.nlm.nih.gov/pubmed/36273231
http://dx.doi.org/10.1038/s41598-022-20560-6