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Acinar ATP8b1/LPC pathway promotes macrophage efferocytosis and clearance of inflammation during chronic pancreatitis development

Noninflammatory clearance of dying cells by professional phagocytes, termed efferocytosis, is fundamental in both homeostasis and inflammatory fibrosis disease but has not been confirmed to occur in chronic pancreatitis (CP). Here, we investigated whether efferocytosis constitutes a novel regulatory...

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Detalles Bibliográficos
Autores principales: Yang, Wan-jun, Cao, Rong-chang, Xiao, Wang, Zhang, Xiao-lou, Xu, Hao, Wang, Meng, Zhou, Zhi-tao, Chen, Huo-ji, Xu, Jia, Chen, Xue-mei, Zeng, Jun-ling, Li, Shu-ji, Luo, Min, Han, Yan-jiang, Yang, Xiao-bing, Feng, Guo-dong, Lu, Yu-heng, Ni, Yuan-yuan, Wu, Chan-gui, Bai, Jun-jie, Yuan, Zi-qi, Jin, Jin, Zhang, Guo-wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588032/
https://www.ncbi.nlm.nih.gov/pubmed/36273194
http://dx.doi.org/10.1038/s41419-022-05322-6