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Epigenetic control of chromosome-associated lncRNA genes essential for replication and stability

ASARs are long noncoding RNA genes that control replication timing of entire human chromosomes in cis. The three known ASAR genes are located on human chromosomes 6 and 15, and are essential for chromosome integrity. To identify ASARs on all human chromosomes we utilize a set of distinctive ASAR cha...

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Detalles Bibliográficos
Autores principales: Heskett, Michael B., Vouzas, Athanasios E., Smith, Leslie G., Yates, Phillip A., Boniface, Christopher, Bouhassira, Eric E., Spellman, Paul T., Gilbert, David M., Thayer, Mathew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588035/
https://www.ncbi.nlm.nih.gov/pubmed/36273230
http://dx.doi.org/10.1038/s41467-022-34099-7