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Potential effects of metal ion induced two-state allostery on the regulatory mechanism of add adenine riboswitch

Riboswitches normally regulate gene expression through structural changes in response to the specific binding of cellular metabolites or metal ions. Taking add adenine riboswitch as an example, we explore the influences of metal ions (especially for K(+) and Mg(2+) ions) on the structure and dynamic...

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Detalles Bibliográficos
Autores principales: Bao, Lei, Kang, Wen-Bin, Xiao, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588036/
https://www.ncbi.nlm.nih.gov/pubmed/36273041
http://dx.doi.org/10.1038/s42003-022-04096-z