Epithelial–mesenchymal transition inhibition by metformin reduces melanoma lung metastasis in a murine model

Melanoma is an aggressive cancer with fast metastatic spread and reduced survival time. One common event during the neoplastic progression is the epithelial–mesenchymal transition (EMT), which enhances invasiveness, cell migration, and metastasis. In this study, we investigated the effects of metfor...

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Detalles Bibliográficos
Autores principales: Veloso, Emerson Soares, de Carvalho, Bárbara Andrade, de Souza Silva, Felipe Henrique, Ribeiro, Thaís Salviana, Lima, Bruna Mendes, Almeida, Camila Pereira, da Silva, Vítor Henrique Soares Romão, Rocha, Sara Aparecida, de Araújo Campos, Marina Rios, Del Puerto, Helen Lima, Ferreira, Enio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588059/
https://www.ncbi.nlm.nih.gov/pubmed/36273071
http://dx.doi.org/10.1038/s41598-022-22235-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588059/
https://www.ncbi.nlm.nih.gov/pubmed/36273071
http://dx.doi.org/10.1038/s41598-022-22235-8

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