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Single-cell transcriptomic analysis highlights origin and pathological process of human endometrioid endometrial carcinoma

Endometrial cancers are complex ecosystems composed of cells with distinct phenotypes, genotypes, and epigenetic states. Current models do not adequately reflect oncogenic origin and pathological progression in patients. Here we use single-cell RNA sequencing to profile cells from normal endometrium...

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Detalles Bibliográficos
Autores principales: Ren, Xiaojun, Liang, Jianqing, Zhang, Yiming, Jiang, Ning, Xu, Yuhui, Qiu, Mengdi, Wang, Yiqin, Zhao, Bing, Chen, Xiaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588071/
https://www.ncbi.nlm.nih.gov/pubmed/36273006
http://dx.doi.org/10.1038/s41467-022-33982-7