Cargando…

Tcf-1 protects anti-tumor TCR-engineered CD8(+) T-cells from GzmB mediated self-destruction

BACKGROUND: T-cell longevity is undermined by antigen-driven differentiation programs that render cells prone to attrition through several mechanisms. CD8 (+ )T cells that express the Tcf-1 transcription factor have undergone limited differentiation and exhibit stem-cell-like replenishment functions...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zangari, Brendan, Tsuji, Takemasa, Matsuzaki, Junko, Mohammadpour, Hemn, Eppolito, Cheryl, Battaglia, Sebastiano, Ito, Fumito, Chodon, Thinle, Koya, Richard, Robert McGray, A. J., Odunsi, Kunle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588092/ https://www.ncbi.nlm.nih.gov/pubmed/35460379 http://dx.doi.org/10.1007/s00262-022-03197-2

Ejemplares similares

Correction to: Tcf‑1 protects anti‑tumor TCR‑engineered CD8(+) T‑cells from GzmB mediated self‑destruction
por: Zangari, Brendan, et al.
Publicado: (2022)

A rare population of tumor antigen-specific CD4(+)CD8(+) double-positive αβ T lymphocytes uniquely provide CD8-independent TCR genes for engineering therapeutic T cells
por: Matsuzaki, Junko, et al.
Publicado: (2019)

CXCR6 by increasing retention of memory CD8(+) T cells in the ovarian tumor microenvironment promotes immunosurveillance and control of ovarian cancer
por: Muthuswamy, Ravikumar, et al.
Publicado: (2021)

Caspase-Dependent Inhibition of Mousepox Replication by gzmB
por: Pardo, Julián, et al.
Publicado: (2009)

Influences of miR-378a-3p on the Pathogenesis of Allergic Rhinitis via GzmB-Mediated Inflammatory Reaction
por: Wang, Xuping, et al.
Publicado: (2022)

LAG3 and PD1 co-inhibitory molecules collaborate to limit CD8(+) T cell signaling and dampen antitumor immunity in a murine ovarian cancer model
por: Huang, Ruea-Yea, et al.
Publicado: (2015)

Identification of Claudin 6-specific HLA class I- and HLA class II-restricted T cell receptors for cellular immunotherapy in ovarian cancer
por: Matsuzaki, Junko, et al.
Publicado: (2022)

Efficient identification of neoantigen-specific T-cell responses in advanced human ovarian cancer
por: Liu, Song, et al.
Publicado: (2019)

The plant protection preparation GZM improves crop immunity, yield, and quality
por: Sun, Yunhao, et al.
Publicado: (2023)

WHSC1/NSD2 regulates immune infiltration in prostate cancer
por: Want, Muzamil Y, et al.
Publicado: (2021)

Split T Cell Tolerance against a Self/Tumor Antigen: Spontaneous CD4(+) but Not CD8(+) T Cell Responses against p53 in Cancer Patients and Healthy Donors
por: Tsuji, Takemasa, et al.
Publicado: (2011)

Oncolytic Maraba virus armed with tumor antigen boosts vaccine priming and reveals diverse therapeutic response patterns when combined with checkpoint blockade in ovarian cancer
por: McGray, A. J. Robert, et al.
Publicado: (2019)

Galectin-3 expression in donor T cells reduces GvHD severity and lethality after allogeneic hematopoietic cell transplantation
por: Mohammadpour, Hemn, et al.
Publicado: (2023)

Genetic engineering of T cells with receptors from NY-ESO-1-specific tumor-recognizing CD4+ T cell as a novel approach for adoptive T cell therapy
por: Matsuzaki, Junko, et al.
Publicado: (2015)

Neoantigens retention in patient derived xenograft models mediates autologous T cells activation in ovarian cancer
por: Want, Muzamil Yaqub, et al.
Publicado: (2019)

Characterization of Postinfusion Phenotypic Differences in Fresh Versus Cryopreserved TCR Engineered Adoptive Cell Therapy Products
por: Nowicki, Theodore S., et al.
Publicado: (2018)

CTLA4 blockade increases Th17 cells in patients with metastatic melanoma
por: von Euw, Erika, et al.
Publicado: (2009)

Compensatory upregulation of PD-1, LAG-3, and CTLA-4 limits the efficacy of single-agent checkpoint blockade in metastatic ovarian cancer
por: Huang, Ruea-Yea, et al.
Publicado: (2016)

Fidelity of human ovarian cancer patient-derived xenografts in a partially humanized mouse model for preclinical testing of immunotherapies
por: Odunsi, Adekunle, et al.
Publicado: (2020)

Direct tumor recognition by a human CD4(+) T-cell subset potently mediates tumor growth inhibition and orchestrates anti-tumor immune responses
por: Matsuzaki, Junko, et al.
Publicado: (2015)

Immuno-stimultory/regulatory gene expression patterns in advanced ovarian cancer
por: Eng, Kevin H., et al.
Publicado: (2015)

Association of GZMB polymorphisms and susceptibility to non-segmental vitiligo in a Korean population
por: Jeong, Ki-Heon, et al.
Publicado: (2021)

Expression and Immune Responses to MAGE Antigens Predict Survival in Epithelial Ovarian Cancer
por: Daudi, Sayeema, et al.
Publicado: (2014)

Analysis of Gzmb(Cre) as a Model System for Gene Deletion in the Natural Killer Cell Lineage
por: Xu, Yiying, et al.
Publicado: (2015)

Genetic polymorphisms of GZMB and vitiligo: A genetic association study based on Chinese Han population
por: Xu, Meifeng, et al.
Publicado: (2018)

A common genetic variation in GZMB may associate with cancer risk in patients with Lynch syndrome
por: Grolmusz, Vince Kornél, et al.
Publicado: (2023)

Sublethal Radiation Affects Antigen Processing and Presentation Genes to Enhance Immunogenicity of Cancer Cells
por: Punnanitinont, Achamaporn, et al.
Publicado: (2020)

Tumor-infiltrating T lymphocyte clonality predicts prognosis in human ovarian cancer
por: Tsuji, Takemasa, et al.
Publicado: (2013)

BiTE secretion by adoptively transferred stem-like T cells improves FRα+ ovarian cancer control
por: McGray, A J Robert, et al.
Publicado: (2023)

Clonality and antigen-specific responses shape the prognostic effects of tumor-infiltrating T cells in ovarian cancer
por: Tsuji, Takemasa, et al.
Publicado: (2020)

Expression of the GZMB Gene Polymorphism, SNP rs8192917, in 990 Han Chinese Patients with Postoperative Keloids
por: Wen, Xiulin, et al.
Publicado: (2022)

A prime/boost vaccine platform efficiently identifies CD27 agonism and depletion of myeloid-derived suppressor cells as therapies that rationally combine with checkpoint blockade in ovarian cancer
por: McGray, A. J. R., et al.
Publicado: (2021)

Suppressed expression of miR-378 targeting gzmb in NK cells is required to control dengue virus infection
por: Liu, Shuyan, et al.
Publicado: (2016)

Long Non-coding RNA LINC02474 Affects Metastasis and Apoptosis of Colorectal Cancer by Inhibiting the Expression of GZMB
por: Du, Tiantian, et al.
Publicado: (2021)

Tuberculosis infection related hemophagocytic lymphohistiocytosis diagnosed in patient with GZMB mutation: A case report and literature review
por: Wang, Zhenhao, et al.
Publicado: (2022)

Reprogramming the tumor microenvironment leverages CD8(+) T cell responses to a shared tumor/self antigen in ovarian cancer
por: Mistarz, Anna, et al.
Publicado: (2023)

Tumor cell culture on collagen–chitosan scaffolds as three-dimensional tumor model: A suitable model for tumor studies
por: Mahmoudzadeh, Aziz, et al.
Publicado: (2016)

A rare subset of skin-tropic regulatory T cells expressing Il10/Gzmb inhibits the cutaneous immune response
por: Ikebuchi, Ryoyo, et al.
Publicado: (2016)

Modulation of Cell Signaling Networks after CTLA4 Blockade in Patients with Metastatic Melanoma
por: Comin-Anduix, Begoña, et al.
Publicado: (2010)

C1QA, C1QB, and GZMB are novel prognostic biomarkers of skin cutaneous melanoma relating tumor microenvironment
por: Liang, Zhuoshuai, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_q3pn6fnlfh1sen5d5r0ej906od