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D-cysteine ethyl ester and D-cystine dimethyl ester reverse the deleterious effects of morphine on arterial blood-gas chemistry and Alveolar-arterial gradient in anesthetized rats

We determined whether intravenous injections of the membrane-permeable ventilatory stimulants, D-cysteine ethyl ester (ethyl (2 S)– 2-amino-3-sulfanylpropanoate) (D-CYSee) and D-cystine dimethyl ester (methyl (2 S)– 2-amino-3-[[(2 S)– 2-amino-3-methoxy-3-oxopropyl]disulfanyl] propanoate) (D-CYSdime)...

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Detalles Bibliográficos
Autores principales: Getsy, Paulina M., Young, Alex P., Grossfield, Alan, Seckler, James M., Wilson, Christopher G., Gaston, Benjamin, Bates, James N., Lewis, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588175/
https://www.ncbi.nlm.nih.gov/pubmed/35447347
http://dx.doi.org/10.1016/j.resp.2022.103912