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The role of whole-brain radiotherapy (WBRT) in primary central nervous system lymphoma: is it an alternative to ASCT for consolidation following HD-methotrexate based induction in low-income settings?

BACKGROUND: Primary central nervous system lymphoma (PCNSL) is a rare and aggressive malignancy. Although potentially curable, its prognosis remains dismal. Its treatment is based on high-doses of methotrexate (HD-MTX) and rituximab, followed by consolidation therapy with whole-brain radiotherapy (W...

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Detalles Bibliográficos
Autores principales: de Pádua Covas Lage, Luís Alberto, Araújo Soares, Vinícius, Meneguin, Thales Dalessandro, Culler, Hebert Fabrício, Reichert, Cadiele Oliana, Jacomassi, Mayara D’Auria, Reis, Diego Gomes Cândido, Zerbini, Maria Cláudia Nogueira, de Oliveira Costa, Renata, Rocha, Vanderson, Pereira, Juliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588209/
https://www.ncbi.nlm.nih.gov/pubmed/36273167
http://dx.doi.org/10.1186/s13014-022-02142-y