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Identification of DNA methylation-regulated differentially expressed genes in RA by integrated analysis of DNA methylation and RNA-Seq data

OBJECTIVE: To identify novel DNA methylation-regulated differentially expressed genes (MeDEGs) in RA by integrated analysis of DNA methylation and RNA-Seq data. METHODS: The transcription and DNA methylation profiles of 9 RA and 15 OA synovial tissue were generated by RNA-Seq and Illumina 850K DNA m...

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Detalles Bibliográficos
Autores principales: Zhang, Runrun, Chang, Cen, Jin, Yehua, Xu, LingXia, Jiang, Ping, Wei, Kai, Xu, Linshuai, Guo, Shicheng, Sun, Songtao, He, Dongyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588210/
https://www.ncbi.nlm.nih.gov/pubmed/36273177
http://dx.doi.org/10.1186/s12967-022-03664-5