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FoxP3 expression by retinal pigment epithelial cells: transcription factor with potential relevance for the pathology of age-related macular degeneration

BACKGROUND: Forkhead-Box-Protein P3 (FoxP3) is a transcription factor and marker of regulatory T cells, converting naive T cells into Tregs that can downregulate the effector function of other T cells. We previously detected the expression of FoxP3 in retinal pigment epithelial (RPE) cells, forming...

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Detalles Bibliográficos
Autores principales: Alfaar, Ahmad Samir, Stürzbecher, Lucas, Diedrichs-Möhring, Maria, Lam, Marion, Roubeix, Christophe, Ritter, Julia, Schumann, Kathrin, Annamalai, Balasubramaniam, Pompös, Inga-Marie, Rohrer, Bärbel, Sennlaub, Florian, Reichhart, Nadine, Wildner, Gerhild, Strauß, Olaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588251/
https://www.ncbi.nlm.nih.gov/pubmed/36273134
http://dx.doi.org/10.1186/s12974-022-02620-w