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Crim1 inhibits angiotensin II-induced hypertrophy and preserves Kv4.2 expression in cardiomyocytes

OBJECTIVE(S): Angiotensin II (Ang II) plays a key role in the regulation of myocardial hypertrophy via downstream cysteine-rich transmembrane bone morphogenetic protein regulator 1 (Crim1). However, it is still unclear whether Crim1 is involved in ionic channel remodeling. The study aimed to explore...

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Detalles Bibliográficos
Autores principales: He, Jionghong, Xia, Guiling, Yang, Long, Jiang, Zhi, Yang, Ying, Huo, Zhaomei, Guo, Chuxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588311/
https://www.ncbi.nlm.nih.gov/pubmed/36311192
http://dx.doi.org/10.22038/IJBMS.2022.61459.13602