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Inhibition of FABP4 attenuates cardiac fibrosis through inhibition of NLRP3 inflammasome activation

OBJECTIVE(S): Cardiac fibrosis is a key biological process of cardiac remodeling and heart failure. Fatty acid-binding protein 4 (FABP4) is a lipid-binding protein that can regulate glucose and lipid homeostasis, and its expression was elevated in heart failure. However, whether FABP4 is involved in...

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Detalles Bibliográficos
Autores principales: Zhu, Xi, Zhang, Xiaogang, Cong, Xinpeng, Zhu, Luoning, Ning, Zhongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588312/
https://www.ncbi.nlm.nih.gov/pubmed/36311201
http://dx.doi.org/10.22038/IJBMS.2022.64499.14186