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Mesenchymal stem cells cause induction of granulocyte differentiation of rat bone marrow C-kit(+) hematopoietic stem cells through JAK3/STAT3, ERK, and PI3K signaling pathways

OBJECTIVE(S): Hematopoietic stem cells (HSCs) are the cells that give rise to different types of blood cells during the hematopoiesis process. Mesenchymal stromal cells (MSCs) as key elements in the bone marrow (BM) niche interact with hematopoietic progenitor cells (HPCs) by secreting cytokines, wh...

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Detalles Bibliográficos
Autores principales: Fathi, Ezzatollah, Mesbah-Namin, Seyed Alireza, Vietor, Ilja, Farahzadi, Raheleh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588313/
https://www.ncbi.nlm.nih.gov/pubmed/36311196
http://dx.doi.org/10.22038/IJBMS.2022.66737.14633