Ameliorating effects of ramelteon on oxidative stress, inflammation, apoptosis, and autophagy markers in methotrexate-induced cerebral toxicity

OBJECTIVE(S): Methotrexate (MTX) is a widely used chemotherapeutic agent that, however, is known to have serious side effects such as neurotoxicity. In the present study, we aimed to evaluate the possible favorable effects of ramelteon (RMLT) on MTX-induced cerebral toxicity. MATERIALS AND METHODS:...

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Detalles Bibliográficos
Autores principales: Aslankoc, Rahime, Savran, Mehtap, Doğuç, Duygu Kumbul, Sevimli, Murat, Tekin, Hale, Kaynak, Mine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588322/
https://www.ncbi.nlm.nih.gov/pubmed/36311194
http://dx.doi.org/10.22038/IJBMS.2022.62955.13913

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588322/
https://www.ncbi.nlm.nih.gov/pubmed/36311194
http://dx.doi.org/10.22038/IJBMS.2022.62955.13913

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