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Effects of Sensitized Sorafenib with a Paeoniflorin and Geniposide Mixture on Liver Cancer via the NF-κB-HIF-2α-SerpinB3 Pathway

PURPOSE: This study focused on determining the anticancer effect of paeoniflorin and geniposide mixture (PFGS) combined with sorafenib (Sor) in hepatocellular carcinoma (HCC) and, in particular, whether PFGS increases the antitumor effect of Sor by modulating the NF-κB/HIF-2α/SerpinB3 pathway. METHO...

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Detalles Bibliográficos
Autores principales: Li, Jun-Fei, Zheng, Xiao-Rong, Zhang, Hong-Yan, Shen, Chang-Ming, Shen, Guo-xin, Jiang, Jian-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588328/
https://www.ncbi.nlm.nih.gov/pubmed/36285158
http://dx.doi.org/10.1155/2022/1911311